Primary Cell Cultures as Models of Prostate Cancer Development

Project Description

In studies of prostate cancer, researchers have used cell lines generated from patients with the most virulent forms of cancer - the kind that has metastasized to invade bone or lymph nodes. But these do not have the same characteristics as cells that come from a localized prostate tumor. The goal of our laboratory work is to develop a cancer cell line that will have the characteristics of the prostate tumor "in vivo." Having this new source of a prostate cancer cell line will benefit prostate cancer research, including the development of drugs. To accomplish this goal we are generating prostate cancer cell lines from tumor tissue of a prostatectomy specimen. The genotypes will be analyzed, and the cell lines taken from the "in vivo" tumor will be used in future research.

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Tumor Microenvironment

Tumor Microenvironment

Is it possible to develop a vaccine that would help patients develop an immune response to prosate cancer?
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Radio Hystopathological Correlation

The potential role of prostate MRI has in recent years expanded significantly, and there is great hope that mpMRI can help address two major problems encountered when treating prostate cancer.
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Poly-ICLC

Poly-ICLC Prostate Cancer Vaccine
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Primary Cell Cultures Care

Primary Cell Cultures as Models of Prostate Cancer Development
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Inflammation & Prostate Cancer

Inflammation and its impact on Prostate Cancer Aggressiveness
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GU Immunotherapy

GU Immunotherapy

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